Rick Eisenstein
PROFESSOR
Department of Nutrition Sciences
University of Wisconsin-Madison
United States of America
Biography
Dr.RICK EISENSTEIN pursued his academic qualification in year-2004-08 J.H. & E.M. Billings-Bascom Professorship in Nutrition 1999 J.H. & E.M. Billings-Bascom Professorship in Nutrition 1998 Mead Johnson Award, American Institute of Nutrition RESEARCH SUMMARY: His research is aimed at elucidating the mechanisms by which mammalian iron homeostasis is maintained in response to specific physiological and pathological situations. Iron is crucial to cell viability because it is a component of proteins that function in a number of physiological processes including respiration and cell division. However, excess iron can be toxic because it participated in the production of potentially lethal oxidizing agents. Mammals use a number of specific proteins to promote the specific and safe transport, uptake and storage of iron.
Research Interest
elucidating the mechanisms by which mammalian iron homeostasis is maintained in response to specific physiological and pathological situations.
Publications
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Pondarré, C., Antiochos, B., Campagna, D.R., Clarke, S.L., Greer, E.L., Deck, K.M., McDonald, A., Han, A-p., Medlock, A., Kutok, J.L., Anderson, S.A., Eisenstein, R.S., and Fleming M.D. (2006) The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulphur cluster biogenesis. Human Mol. Genet.15:953-964>
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Anderson, S.A., Nizzi, C.P., Chang, Yuan-I., Deck, K.M., Schmidt, P., Galy, B., Broman, A.T., Kendziorski, C., Hentze, M.W., Fleming, M.D., Zhang, J. and Eisenstein, R.S. (2013) The IRP1-HIF2a Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption. Cell Metabolism 17:282-290.
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Anderson CP, Shen M, Eisenstein RS, Leibold EA.(2012) Mammalian iron metabolism and its control by iron regulatory proteins. Biochim Biophys Acta. 1823:1468-8.
