Christine Garcia
Professor
Internal Medicine
UT Southwestern Medical Center
United States of America
Biography
Christine Kim Garcia received both her medical and graduate degrees from the University of Texas Southwestern Medical Center in 1996 and is currently a Professor of Internal Medicine and a member of the Division of Pulmonary and Critical Care Medicine. She cares for patients seen in the UT Southwestern Advanced Lung Disease Clinic, Clements University Hospital and Parkland Memorial Hospital. She is also a member of the Eugene McDermott Center for Human Growth and Development. She directs a research laboratory that focuses on defining the genetic underpinnings of adult-onset lung disease. Her laboratory has discovered rare mutations in different genes that lead to inherited forms of interstitial lung disease. These discoveries have highlighted the link between idiopathic pulmonary fibrosis (IPF), aging and telomere dysfunction. She is a member of the American Society for Clinical Investigation.
Research Interest
Genetic determinants of adult lung disease Telomere-related pulmonary fibrosis
Publications
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Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation. Stuart BD, Lee JS, Kozlitina J, Noth I, Devine MS, Glazer CS, Torres F, Kaza V, Girod CE, Jones KD, Elicker BM, Ma SF, Vij R, Collard HR, Wolters PJ, Garcia CK Lancet Respir Med 2014 Jun
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Effect of Leukocyte Telomere Length on Total and Regional Brain Volumes in a Large Population-Based Cohort. King KS, Kozlitina J, Rosenberg RN, Peshock RM, McColl RW, Garcia CK JAMA Neurol 2014 Aug
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Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening. Stuart BD, Choi J, Zaidi S, Xing C, Holohan B, Chen R, Choi M, Dharwadkar P, Torres F, Girod CE, Weissler J, Fitzgerald J, Kershaw C, Klesney-Tait J, Mageto Y, Shay JW, Ji W, Bilguvar K, Mane S, Lifton RP, Garcia CK Nat. Genet. 2015 May 47 5 512-7
