Anthony V. Nicola
veterinary microbiology and pathology
Washington State University
United States of America
BA: Drew University PhD: University of Pennsylvania Post-doctoral: Yale University and Swiss Federal Institute of Technology
Herpesviruses are a significant cause of morbidity and mortality in humans and animals worldwide. Herpes simplex virus (HSV) remains a major global pathogen causing oral and genital infections, blindness, encephalitis, and neonatal infections. The long-term goal of my laboratory is to understand the molecular processes that herpesviruses use to gain entry into host cells. HSV causes lifelong, latent infection for which there is no cure. A better understanding of how HSV interacts with the cell during the initial stages of infection will identify novel intervention strategies and antiviral drug targets. We utilize a combination of cellular, molecular, biochemical, and microscopic approaches to delineate the step-by-step itinerary of the incoming virus.