Celeste M. Karch
Assistant Professor
Nuerology
Washington University School of Medicine
United States of America
Biography
Assistant Professor Psychiatry Neurology
Research Interest
neurodegeneration, neurogenetics, Alzheimer`s disease, frontotemporal dementia, tau, amyloid precursor protein, induced pluripotent stem cells (iPSC), cell and molecular biology, molecular mechanisms
Publications
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Karch CM, Ezerskiy L, Redaelli V, Giovagnoli AR, Tiraboschi P, Pelliccioni G, Pelliccioni P, Kapetis D, D`Amato I, Piccoli E, et al. Missense mutations in progranulin gene associated with frontotemporal lobar degeneration: study of pathogenetic features. Neurobiol Aging. 2016 Feb;38:215.e1-12. doi: 10.1016/j.neurobiolaging.2015.10.029. Epub 2015 Nov 2. PubMed PMID: 26652843; PubMed Central PMCID: PMC4738142.
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Wakle-Prabagaran M, Lorca RA, Ma X, Stamnes SJ, Amazu C, Hsiao JJ, Karch CM, Hyrc KL, Wright ME, England SK. BKCa channel regulates calcium oscillations induced by alpha-2-macroglobulin in human myometrial smooth muscle cells. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):E2335-44. doi: 10.1073/pnas.1516863113. Epub 2016 Apr 4. PubMed PMID: 27044074; PubMed Central PMCID: PMC4843459.
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Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, et al. Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. JAMA Neurol. 2016 Jun 1;73(6):691-7. doi: 10.1001/jamaneurol.2016.0150. PubMed PMID: 27088644; PubMed Central PMCID: PMC4905783.