Evan D. Kharasch
Washington University School of Medicine
United States of America
Mary B. Shelden Professor Anesthesiology Division of Clinical & Translational Research Director, Division of Clinical & Translational Research Biochemistry and Molecular Biophysics
biomarkers, kidney, mass spectrometry, opiates, pain, translational research
Totah RA, Allen KE, Sheffels P, Whittington D, Kharasch ED. Enantiomeric metabolic interactions and stereoselective human methadone metabolism. J Pharmacol Exp Ther 2007 321:389-99.
Totah RA, Sheffels P, Roberts T, Whittington D, Thummel K, Kharasch ED. Role of CYP2B6 in stereoselective human methadone metabolism. Anesthesiology 2008 108:363-74.
Kharasch ED, Mitchell D, Coles R, Blanco R. Rapid clinical induction of hepatic cytochrome P4502B6 activity by ritonavir. Antimicrob Agents Chemother. 2008 52(5):1663-9.