Medical Sciences

Medical Sciences Experts

Evan D. Kharasch

Washington University School of Medicine
United States of America

Evan D. Kharasch


Mary B. Shelden Professor Anesthesiology Division of Clinical & Translational Research Director, Division of Clinical & Translational Research Biochemistry and Molecular Biophysics

Research Interest

biomarkers, kidney, mass spectrometry, opiates, pain, translational research


  • Totah RA, Allen KE, Sheffels P, Whittington D, Kharasch ED. Enantiomeric metabolic interactions and stereoselective human methadone metabolism. J Pharmacol Exp Ther 2007 321:389-99.

  • Totah RA, Sheffels P, Roberts T, Whittington D, Thummel K, Kharasch ED. Role of CYP2B6 in stereoselective human methadone metabolism. Anesthesiology 2008 108:363-74.

  • Kharasch ED, Mitchell D, Coles R, Blanco R. Rapid clinical induction of hepatic cytochrome P4502B6 activity by ritonavir. Antimicrob Agents Chemother. 2008 52(5):1663-9.

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