Tim B. Schedl

Biography

We are studying two processes that are critical for germ cell development: 1) the decision between the stem cell fate vs. initiate meiotic development and 2) control of progression through meiotic prophase and coordination with oogenesis. Little is know about these processes in any animal. We utilize C. elegans because of its transparency, tractable genetics and functional genomics. Cell-cell signaling regulates the two germline processes.

Research Interest

Working on germ cells, C. elegans, genetics, development, functional genomics. Our hope is that the ability to rapidly associate genotype with phenotype in C. elegans can be exploited to expand the number of genes and variants that contribute to human disease.