Terry L.orr-weaver
Professor
BIOLOGY
Whitehead Institute for Biomedical Research
United States of America
Biography
Orr-Weaver is a professor of biology at MIT. She came to Whitehead Institute and MIT in 1987, and held the Latham Family Career Development Chair from 1991 to 1994. Orr-Weaver received her PhD in biological chemistry from Harvard University in 1984, and was named a Jane Coffin Child Memorial Fund Fellow in 1984 and a Searle Scholar in 1988. She has served as chair of the Scientific Advisory Committee of the Damon Runyon Cancer Research Foundation and president of the Genetics Society of America. In 2006, she was elected a Fellow of the American Academy of Microbiology and a member of the National Academy of Sciences. In 2007, she was appointed an American Cancer Society Research Professor. In 2008 she was appointed a senior advisor of the Genetics Society of America and elected president of the National Drosophila Board
Research Interest
Whitehead Member Terry Orr-Weaver investigates the mechanisms that control the sequence of events during which a cell duplicates its DNA and divides in two. Studies in the Orr-Weaver lab have illuminated fundamental aspects of this process, known as the cell cycle, and shed new light on a broad range of diseases caused by breakdowns in cell division, including cancer and certain birth defects.
Publications
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Edgar, B. A., & Orr-Weaver, T. L. (2001). Endoreplication cell cycles: more for less. Cell, 105(3), 297-306.
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Orr-Weaver, T. L., Szostak, J. W., & Rothstein, R. J. (1981). Yeast transformation: a model system for the study of recombination. Proceedings of the National Academy of Sciences, 78(10), 6354-6358.
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Szostak, J. W., Orr-Weaver, T. L., Rothstein, R. J., & Stahl, F. W. (1983). The double-strand-break repair model for recombination. Cell, 33(1), 25-35.
