Hemlata Mistry
Associate Professor
BIOLOGY
Widener University
United States of America
Biography
earned my PhD from the University of Cambridge, UK, where I investigated the genetic mechanisms regulated by G-proteins that are important for cell communication. I continued my training as a postdoctoral research associate at Washington University School of Medicine in St. Louis, Missouri, working on genetic and developmental mechanisms underlying the generation of cell diversity in the nervous system of Drosophila.
Research Interest
development of fruit flies (Drosophila melanogaster). The embryonic Drosophila central nervous system similar to the human spinal cord is a paradigm for understanding the cellular processes and genetic pathways regulating the formation and maintenance of a diverse population of nerve cells. My research interests include investigating the role of RNA degradation in Drosophila development, investigating the impact of wounding in the Drosophila embryonic central nervous system, and investigating the effect of protein degradation on the activity of different transcription factors in neuronal fate decisions during nervous system development in Drosophila.
Publications
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Shaffer, C., Mistry, H., et al.(2014). A course-based research experience: How benefits change with increased investment in instructional time. CBE Life Sciences Education 13(1), 111–130.
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Lacin, H., Rusch, J., Yeh, R.T., Fujioka, M., Wilson, B.A., Zhu, Y., Mistry, H., Jaynes, J.B., & Skeath J.B. (2014). Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of Nitric Oxide Synthase and FoxD. Developmental Biology, 388(1), 117–133.
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A. Burcu Babaoglan, A., O'Connor-Giles, K.M., Mistry, H., Schickedanz, A., Wilson, BA, & Skeath, JB. (2009). Sanpodo: A context-dependent activator and inhibitor of Notch signaling during asymmetric divisions. Development 136(24), 4089–4098.
