United States of America
The Abdel-Mohsen laboratory investigates the role of host-virus interactions in persistence and immunopathogenesis of HIV infection by combining virological, glycobiological, and immune-based basic and translational research. The multidisciplinary studies aim to develop novel approaches to enhance immune function and control/eradicate HIV.
Abdel-Mohsen’s research focuses on diverse aspects of HIV pathogenesis, including HIV latency, host-virus interactions, intrinsic immunity, and HIV sequence diversity.
3) Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T. TIGIT marks exhausted T cells, correlates with disease progression, and serves as a target for immune restoration in HIV and SIV infection. PLoS pathogens. 2016 Jan 7;12(1):e1005349.
2) Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB. Human galectin-9 is a potent mediator of HIV transcription and reactivation. PLoS pathogens. 2016 Jun 2;12(6):e1005677.
1) Leal FE, Premeaux TA, Abdel-Mohsen M, Ndhlovu LC. Role of Natural Killer Cells in HIV-Associated Malignancies. Frontiers in Immunology. 2017;8.