Jeffrey Bryant Travers
Department of PHARMACOLOGY & TOXICOLOGY
Wright State University
United States of America
Professor and Chair, Pharmacology & Toxicology Professor, Dermatology works in Health Sciences Bldg 207, 3640 Colonel Glenn Hwy, Dayton, OH 45435-0001
He have the good fortune to be both a pharmacologist and a practicing dermatologist. In addition to serving as Professor and Chair of the Department of Pharmacology & Toxicology, he is Professor of Dermatology and also hold a part-time 5/8th Staff Physician at the Dayton VA. he see dermatology patients in both the WSU Department of Dermatology as well as at the Dayton VA Medical Center. There are two major research interests of his laboratory. First is the the pharmacology the lipid mediator Platelet-activating Factor (PAF). They have demonstrated that PAF and related oxidized glycerophosphocholines (Ox-GPCs) are produced in response to numerous pro-oxidative environmental stimuli from UV radiation to chemotherapy and cigarette smoke exposure. PAF-receptor agonists exert acute pro-inflammatory and delayed immunosuppressive effects. Their models range from cultured cells to mice to humans.
Sahu, RP, Y Yao, RL Konger, and JB Travers. Platelet-activating Factor does not Mediate UVB-induced Local Immune Suppression. Photochem. Photobiol. 88:490-93, 2012. PMC3292709
Travers, J., M. Al-Hassani, Y. Yao, R. Konger and J.B. Travers. Ultraviolet B Radiation of Human Skin Generates Platelet-activating Factor Receptor Agonists. Photochem. Photobiol. 86:949-954, 2010. PMC: 20492565.
Wolverton, J. E., M. Al-Hassani, Y. Yao, and J.B. Travers. Epidermal platelet-activating factor activation and ultraviolet B radiation result in synergistic tumor necrosis factor alpha production. Photochem. Photobiol. 86:231-235, 2010. PMC2875301.