Weiwen Long
Ph.D.
Biochemistry and Molecular Biology
Wright State University
United States of America
Biography
Ph.D.: 2005 Tulane University (Dr. Frank E. Jones) Postdoctoral: Baylor College of Medicine (Dr. Bert W. O’Malley)
Research Interest
His research interests and expertise have been directed to the fields of growth factor signaling, steroid receptor/coactivator signaling, and the interplay between these two signaling pathways in cancer progression and metastasis.
Publications
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Liu J, Wang Y, Li L, Zhou L, Wei H, et al. (2013) Site-specific acetylation of the proteasome activator REGgamma directs its heptameric structure and functions. J Biol Chem 288: 16567-78.
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Wang W, Bian K, Vallahabneni S, Zhang B, Wu RC, et al. (2014) ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression. Journal of Cell Physiology 229: 1529-37.
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Liu J, Cho SN, Akkanti B, Jin N, Mao J, et al. (2015) ErbB2 pathway activation upon Smad4 loss promotes lung tumor growth and metastasis. Cell Reports 10: 1599-1613.
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Dasgupta S, Putluri N, Long W, Zhang B, Wang J, et al. (2015) Coactiavtor SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis. Journal of Clinical Investigation 125: 1174-88.
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Ka B, Muppani N, Elkhadragy L, Wang W, Chen T, et al. (2016) ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells. Oncotarget 7: 6665-75.
