Yale Department Of Chemistry
United States of America
B.S. University of Massachusetts, 1984 Ph.D. Brandeis University, 1989
pursuing the generation of heuristic design rules for the construction of molecular structures of reduced hazard. By understanding the detailed mechanism of action of toxicity, it is possible to manipulate the properties regulating pharmacokinetics and pharmacodynamics in ways that reduce or eliminate the target biological endpoint.
J. Kostal, A. Voutchkova-Kostal, P. Anastas, & J.B. Zimmerman. Identifying and designing chemicals with minimal acute aquatic toxicity. Proc Natl Acad Sci USA2014.
A. Bloomfield, S. Sheehan, S. Collom, R. Crabtree, P.T. Anastas. A heterogeneous water oxidation catalyst from dicobalt octacarbonyl and 1,2-bis(diphenylphosphino)ethane. New Journal of Chemistry 2014, 38 (4), 1540-1545.
K. Barta, G. Warner, E.S. Beach, & P.T. Anastas. Depolymerization of organosolv lignin to aromatic compounds over Cu-doped porous metal oxides. Green Chemistry 2014, 16 (1), 191-196.