Ana Maria Cuervo
Professor
Department of Anatomy & Structural Biology, Albert Einstein
Yeshiva University
United States of America
Biography
Ana Maria Cuervo is Professor in Department of Anatomy & Structural Biology, Albert Einstein College of Medicine at Yeshiva University, USA
Research Interest
Research Interests: Understanding the molecular basis of malfunctioning of autophagy (cellular quality control system) with age and the contribution of defects on this cellular pathway to neurodegeneration, metabolic disorders and cancer.
Publications
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Cuervo AM, Stephanis L, Freundberg R, Lansbury P, Sulzer D (2004) Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science305 1292-1295.
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Kaushik S, Massey A.C, Kiffin R, Cuervo AM (2006) Role of lysosomal lipid microdomains in the regulation of chaperone-mediated autophagy. EMBO J 25: 3921-3933.
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Zhang C, Cuervo AM (2008) Restoration of chaperone-mediated autophagy in aging improves cellular maintenance and organ function. Nat Med 14: 959-965.