John S. Condeelis
Professor
Department of Anatomy & Structural Biology, Albert Einstein
Yeshiva University
United States of America
Biography
John Condeelis has devised optical microscopes for uncaging, biosensor detection and multiphoton imaging for these studies and has used novel caged-enzymes and biosensors to test, in vivo, the predictions of the invasion signatures regarding the mechanisms of tumor cell dissemination and metastasis. He is one of the founding co-directors of the Integrated Imaging Program dedicated to the integration and validation of clinical imaging platforms, including digital pathology, with high resolution optical imaging in the Gruss Lipper Biophotonics Center. He has authored more than 300 scientific papers on various aspects of his research.
Research Interest
Research Interests: optical physics, cell biology and biophysics, cancer biology and mouse models of cancer. Development of the multiphoton imaging technology used to identify intravasation microenvironments in metastatic tumors
Publications
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Knutsdottir H, Condeelis JS, Palsson E (2015) 3-D individual cell based computational modeling of tumor cell-macrophage paracrine signaling mediated by EGF and CSF-1 gradients. Integr Biol (Camb) 8: 104-119.
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Hughes S.K, Rohani N, Moufarrej MN, Jones JG, Condeelis JS, et al. (2015) Characterization of the expression of the pro-metastatic MenaINV isoform during breast tumor progression. Clin exper metast 33: 249-261.
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Karagiannis GS, Goswami S, Jones JG, Oktay MH, Condeelis JS (2016) Signatures of breast cancer metastasis at a glance. J Cell Sci 129: 1751-1758.
