Medical Sciences

Medical Sciences Experts

David Lopes Cardozo

Assistant Professor
Departmaent of Neurobiology
Harvard Medical School
United States Virgin Islands


A small research effort which involves locating new sources of neural stem cells that have therapeutic potential. I am attempting to isolate neural stem cells from rat and human tissue.

Research Interest

  5,7-Dihydroxytryptamine Adolescent Adult Animals Animals, Newborn Astrocytes Baclofen Base Sequence Caenorhabditis elegans Proteins Calcium Channels Career Choice Carica Cauda Equina Cell Differentiation Cell Membrane Cell Separation Cells, Cultured Chick Embryo Child Child, Preschool Comprehension COS Cells Diffusion Dopamine Dose-Response Relationship, Drug Education, Medical Education, Medical, Undergraduate Educational Measurement Electrophysiology Ergolines Female Fetus Genetic Markers Genome, Plant Genotype Glial Fibrillary Acidic Protein Hedgehog Proteins Homozygote Humans Immunohistochemistry Infant Infant, Newborn Intercellular Signaling Peptides and Proteins Intuition Ion Channels Male Membrane Potentials Mesencephalon Microinjections Microsatellite Repeats Microscopy, Fluorescence Models, Biological Molecular Sequence Data Motor Neurons Multipotent Stem Cells Muscles Mutation Nervous System Neural Stem Cells Neural Tube Defects Neurogenesis Neuroglia Neuromuscular Junction Neurons Neurosciences Nimodipine Oligodendroglia Patch-Clamp Techniques Physiology Potassium Channels Potassium Channels, Voltage-Gated Pregnancy Private Sector Problem-Based Learning Public Sector Quinpirole Rats Rats, Sprague-Dawley Receptors, Dopamine Receptors, GABA-B Self-Fertilization Shaw Potassium Channels Spinal Cord Students, Medical Tetrodotoxin Thymidine Tretinoin


  • Cardozo DL, Bean BP. Voltage-dependent calcium channels in rat midbrain dopamine neurons: modulation by dopamine and GABAB receptors. J Neurophysiol. 1995 Sep; 74(3):1137-48. PMID: 7500139.

  • Elkes DA, Cardozo DL, Madison J, Kaplan JM. EGL-36 Shaw channels regulate C. elegans egg-laying muscle activity. Neuron. 1997 Jul; 19(1):165-74. PMID: 9247272.

  • Cardozo DL. A model for understanding membrane potential using springs. Adv Physiol Educ. 2005 Dec; 29(4):204-7. PMID: 16298957.

  • Cardozo DL, Raymond L, White B. A structured PBL tutorial involving small teams for teaching the human nervous system. Med Teach. 2012; 34(11):e763-71. PMID: 22861351.

  • Jha RM, Liu X, Chrenek R, Madsen JR, Cardozo DL. The postnatal human filum terminale is a source of autologous multipotent neurospheres capable of generating motor neurons. Neurosurgery. 2013 Jan; 72(1):118-29; discussion 129. PMID: 23096415.

  • Jha RM, Chrenek R, Magnotti LM, Cardozo DL. The isolation, differentiation, and survival in vivo of multipotent cells from the postnatal rat filum terminale. PLoS One. 2013; 8(6):e65974. PMID: 23762453; PMCID: PMC3675200.

  • Pinto FO, Pereira MG, Luz LN, Cardozo DL, Ramos HC, Macedo CM. Use of microsatellite markers in molecular analysis of segregating populations of papaya (Carica papaya L.) derived from backcrossing. Genet Mol Res. 2013 Jul 08; 12(3):2248-59. PMID: 23884768.

  • Cardozo DL, Holdsworth PC. Finite-size scaling of the magnetization probability density for the critical Ising model in slab geometry. J Phys Condens Matter. 2016 Apr 27; 28(16):166007. PMID: 27022780.

  • Akil H, Balice-Gordon R, Cardozo DL, Koroshetz W, Posey Norris SM, Sherer T, Sherman SM, Thiels E. Neuroscience Training for the 21st Century. Neuron. 2016 Jun 01; 90(5):917-26. PMID: 27253446.

  • Chrenek R, Magnotti LM, Herrera GR, Jha RM, Cardozo DL. Characterization of the Filum terminale as a neural progenitor cell niche in both rats and humans. J Comp Neurol. 2017 Feb 15; 525(3):661-675. PMID: 27511739.

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